And Glut4 Diabetes
Glut4 Diabetes Exercise Diabetestalk Net The role of glut4 in insulin resistance is an active area of diabetes research. sugar consumption causes the pancreas to secrete too much insulin. insulin triggers the transport of this protein to the cell surface through a complicated signal transduction mechanism involving the phosphorylation and dephosphorylation of proteins and lipids. Insulin and amp-activated protein kinase (ampk) signal pathways are known to be involved in glucose uptake regulation, but the integration of signals between these two pathways in maintaining glucose homeostasis remains mysterious . insulin stimulates glucose uptake into skeletal muscle mainly via the translocation of glucose transporter 4 (glut4) to the plasma membrane . Glucose transporter type 4, also known as solute carrier family 2, facilitated glucose transporter member 4, is a protein encoded, in humans, by the slc2a4 gene. glut4 is the insulin-regulated glucose transporter found primarily in adipose ...